名称 | AI-Edigene® PIK3CA p.E545K Reference Standard |
型号 | CBP10517 |
报价 | ![]() |
特点 | AI-Edigene® PIK3CA p.E545K Reference Standard Plus |
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- 详细内容
CBP10517 | |
Format | Genomic DNA |
Description | PIK3CA E545K is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545K results in increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and is transforming in culture (PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.1633G>A |
AA Change | p.E545K |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100.00% |
Transcript | NM_006218.4 |
Cosmic ID | COSM763 |
Chr position(GRCh37) | chr3:178936091 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |